A year after leaving his former life in the Tojo Clan behind, ex-yakuza Kazuma Kiryu is called back into action when the clan's Fifth Chairman, Yukio Terada, is murdered by assassins from a rival organization, the Omi Alliance. Returning to Kamurocho, Kiryu must find a new chairman for the Tojo Clan and prevent an all-out war between the Tojo and the Omi, bringing him into conflict with Ryuji Goda, the legendary "Dragon Of Kansai" of the Omi Alliance.